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1

Capability Driven Development: An Approach to Designing Digital Enterprises

Bērziša, Solvita, Bravos, George, Gonzalez, Tania Cardona, Czubayko, Ulrich, España, Sergio, Grabis, Jānis, Henkel, Martin, Jokste, Lauma, Kampars, Jânis, Koç, Hasan, Kuhr, Jan-Christian, Llorca, Carl

Journal:

Business & Information Systems Engineering

Year:

2015

Language:

english

File:

PDF, 663 KB

english, 2015

2

ERbB-2 expression is rate-limiting for epidermal growth factor–mediated stimulation of ovarian cancer cell proliferation

Susie S. Hsieh, Claudius Malerczyk, Achim Aigner, Frank Czubayko

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 181 KB

english, 2000

3

P2U nucleotide receptor activation in rat glial cell line induces [Ca2+]i oscillations which depend on cytosolic pH

Uwe Czubayko, Georg Reiser

Journal:

Year:

1996

Language:

english

File:

PDF, 857 KB

english, 1996

4

An FGF-binding protein (FGF-BP) exerts its biological function by parallel paracrine stimulation of tumor cell and endothelial cell proliferation through FGF-2 release

Achim Aigner, Moritz Butscheid, Philip Kunkel, Eberhard Krause, Katrin Lamszus, Anton Wellstein, Frank Czubayko

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 1.49 MB

english, 2001

5

Bioaktive Ribozym/Polyethylenimin-Komplexe: Ein neues Verfahren zum effizienten und spezifischen Targeting tumorrelevanter Genprodukte

A. Aigner, F. Czubayko

Journal:

Chemie Ingenieur Technik

Year:

2002

Language:

english

File:

PDF, 114 KB

english, 2002

6

Morphological classification of the rat lateral cerebellar nuclear neurons by principal component analysis

Fahad Sultan, Uwe Czubayko, Peter Thier

Journal:

The Journal of Comparative Neurology

Year:

2003

Language:

english

File:

PDF, 746 KB

english, 2003

7

Ribozyme-targeting reveals the rate-limiting role of pleiotrophin in glioblastoma

Marius Grzelinski, Nicole Bader, Frank Czubayko, Achim Aigner

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 857 KB

english, 2005

8

Polyethylenimine/small interfering RNA-mediated knockdown of vascular endothelial growth factor in vivo exerts anti-tumor effects synergistically with Bevacizumab

Sabrina Höbel, Ivette Koburger, Matthias John, Frank Czubayko, Philipp Hadwiger, Hans-Peter Vornlocher, Achim Aigner

Journal:

The Journal of Gene Medicine

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

9

Reversal of HER-2 over-expression renders human ovarian cancer cells highly resistant to taxol

Achim Aigner, Susie S Hsieh, Claudius Malerczyk, Frank Czubayko

Journal:

Year:

2000

Language:

english

File:

PDF, 153 KB

english, 2000

10

Characterization of nanoscaled heterogeneities in mechanically alloyed and compacted CuFe

N. Wanderka, U. Czubayko, V. Naundorf, V.A. Ivchenko, A.Ye. Yermakov, M.A. Uimin, H. Wollenberger

Journal:

Ultramicroscopy

Year:

2001

Language:

english

File:

PDF, 467 KB

english, 2001

11

Three-dimensional atom probing of supersaturated mechanically alloyed Cu–20at.% Co

U Czubayko, N Wanderka, V Naundorf, V.A Ivchenko, A.Ye Yermakov, M.A Uimin, H Wollenberger

Journal:

Materials Science and Engineering: A

Year:

2002

Language:

english

File:

PDF, 424 KB

english, 2002

12

Local chemical and structural gradients in the creep deformed superalloy SC16

N. Wanderka, G. Schumacher, U. Czubayko, V. Naundorf, R. Schneider, W. Neumann

Journal:

Materials Science and Engineering: A

Year:

2003

Language:

english

File:

PDF, 695 KB

english, 2003

13

Primary crystals in ZrTiCuNiBe bulk glasses

N Wanderka, U Czubayko, P Schubert-Bischoff, M.-P Macht

Journal:

Materials Science and Engineering: A

Year:

1999

Language:

english

File:

PDF, 556 KB

english, 1999

14

On the effect of purity and orientation on grain boundary motion

D.A. Molodov, U. Czubayko, G. Gottstein, L.S. Shvindlerman

Journal:

Acta Materialia

Year:

1998

Language:

english

File:

PDF, 552 KB

english, 1998

15

Inhibition of fibroblast growth factors

Anton Wellstein, Frank Czubayko

Journal:

Breast Cancer Research and Treatment

Year:

1996

Language:

english

File:

PDF, 836 KB

english, 1996

16

Inhibition of HER-2 by three independent targeting strategies increases paclitaxel resistance of SKOV-3 ovarian carcinoma cells

Shaker Abuharbeid, Jürgen Apel, Gerhard Zugmaier, Cornelius Knabbe, Martin Sander, Sandra Gilbert, Frank Czubayko, Achim Aigner

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2005

Language:

english

File:

PDF, 239 KB

english, 2005

17

Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs

Anja Frömberg, Daniela Gutsch, Daniel Schulze, Claudia Vollbracht, Gabriele Weiss, Frank Czubayko, Achim Aigner

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 367 KB

english, 2011

18

Immunolocalization of an FGF-binding protein reveals a widespread expression pattern during different stages of mouse embryo development

Achim Aigner, Patricio E. Ray, Frank Czubayko, Anton Wellstein

Journal:

Histochemistry and Cell Biology

Year:

2002

Language:

english

File:

PDF, 740 KB

english, 2002

19

A sensitive polymerase chain reaction-based method for detection and quantification of metastasis in human xenograft mouse models

Anastasia Malek, Carlo V. Catapano, Frank Czubayko, Achim Aigner

Journal:

Clinical and Experimental Metastasis

Year:

2010

Language:

english

File:

PDF, 560 KB

english, 2010

20

Influence of triple junctions on grain boundary motion

U. Czubayko, V.G. Sursaeva, G. Gottstein, L.S. Shvindlerman

Journal:

Acta Materialia

Year:

1998

Language:

english

File:

PDF, 1002 KB

english, 1998

21

A secreted FGF-binding protein can serve as the angiogenic switch in human cancer

Czubayko, Frank, Liaudet-Coopman, Emmanuelle D.E., Aigner, Achim, Tuveson, Anne T., Berchem, Guy J., Wellstein, Anton

Journal:

Nature Medicine

Year:

1997

File:

PDF, 497 KB

1997

22

Adenovirus-mediated transduction of ribozymes abrogates HER-2/neu and pleiotrophin expression and inhibits tumor cell proliferation

Czubayko, F, Downing, S G, Hsieh, S S, Goldstein, D J, Lu, P Y, Trapnell, B C, Wellstein, A

Journal:

Year:

1997

Language:

english

File:

PDF, 301 KB

english, 1997

23

Delivery of unmodified bioactive ribozymes by an RNA-stabilizing polyethylenimine (LMW-PEI) efficiently down-regulates gene expression

Aigner, A, Fischer, D, Merdan, T, Brus, C, Kissel, T, Czubayko, F

Journal:

Year:

2002

Language:

english

File:

PDF, 408 KB

english, 2002

24

Expression of a truncated 100 kDa HER2 splice variant acts as an endogenous inhibitor of tumour cell proliferation

Aigner, Achim, Juhl, Hartmut, Malerczyk, Claudius, Tkybusch, Anja, Benz, Christopher C, Czubayko, Frank

Journal:

Year:

2001

Language:

english

File:

PDF, 272 KB

english, 2001

25

The human papillomavirus (HPV) 16 E6 oncoprotein leads to an increase in gene expression of the angiogenic switch molecule FGF-BP in non-immortalized human keratinocytes

Stöppler, Hubert, Malerczyk, Claudius, Block, Katrin, Aigner, Achim, Czubayko, Frank

Journal:

Year:

2001

Language:

english

File:

PDF, 224 KB

english, 2001

26

Ribozyme-targeting of a secreted FGF-binding protein (FGF-BP) inhibits proliferation of prostate cancer cells in vitro and in vivo

Aigner, Achim, Renneberg, Heiner, Bojunga, Jörg, Apel, Jürgen, Nelson, Peter S, Czubayko, Frank

Journal:

Year:

2002

Language:

english

File:

PDF, 286 KB

english, 2002

27

Heregulin-β1 regulates the estrogen receptor-α gene expression and activity via the ErbB2/PI 3-K/Akt pathway

Stoica, Gerald E, Franke, Thomas F, Wellstein, Anton, Morgan, Elisha, Czubayko, Frank, List, Heinz-Joachim, Reiter, Ronald, Martin, Mary Beth, Stoica, Adriana

Journal:

Year:

2003

Language:

english

File:

PDF, 362 KB

english, 2003

28

Heregulin-β1 regulates the estrogen receptor-α gene expression and activity via the ErbB2/PI 3-K/Akt pathway

Stoica, Gerald E, Franke, Thomas F, Wellstein, Anton, Morgan, Elisha, Czubayko, Frank, List, Heinz-Joachim, Reiter, Ronald, Martin, Mary Beth, Stoica, Adriana

Journal:

Year:

2005

Language:

english

File:

PDF, 61 KB

english, 2005

29

Inhibition of endogenous carcinoembryonic antigen (CEA) increases the apoptotic rate of colon cancer cells and inhibits metastatic tumor growth

Thomas Wirth, Edlyn Soeth, Frank Czubayko, Hartmut Juhl

Journal:

Clinical and Experimental Metastasis

Year:

2002

Language:

english

File:

PDF, 153 KB

english, 2002

30

Using grain boundary mobility to characterize aluminum purity

D. A. Molodov, U. Czubayko, G. Gottstein, L. S. Shvindlerman

Journal:

JOM Journal of the Minerals, Metals and Materials Society

Year:

1996

Language:

english

File:

PDF, 454 KB

english, 1996

31

Stabilization of oligonucleotide–polyethylenimine complexes by freeze-drying: physicochemical and biological characterization

Carola Brus, Elke Kleemann, Achim Aigner, Frank Czubayko, Thomas Kissel

Journal:

Journal of Controlled Release

Year:

2004

Language:

english

File:

PDF, 1.01 MB

english, 2004

32

A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes

Stephanie Werth, Beata Urban-Klein, Lige Dai, Sabrina Höbel, Marius Grzelinski, Udo Bakowsky, Frank Czubayko, Achim Aigner

Journal:

Journal of Controlled Release

Year:

2006

Language:

english

File:

PDF, 621 KB

english, 2006

33

Comparison of oxide measurement techniques applied to Ti6Al4V

L. Reissig, U. Czubayko, N. Wanderka, R. Völkl, U. Glatzel

Journal:

Materials Characterization

Year:

2005

Language:

english

File:

PDF, 421 KB

english, 2005

34

In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(–PEG)/siRNA complexes

Anastasia Malek, Olivia Merkel, Ludger Fink, Frank Czubayko, Thomas Kissel, Achim Aigner

Journal:

Toxicology and Applied Pharmacology

Year:

2009

Language:

english

File:

PDF, 860 KB

english, 2009

35

Distribution of boron in Fe-14B before and after primary crystallization

Y. Zhang, U. Czubayko, N. Wanderka, V. Naundorf, F. Zhu, H. Wollenberger

Journal:

Scripta Materialia

Year:

2001

Language:

english

File:

PDF, 274 KB

english, 2001

36

Rhenium distribution in the matrix and near the particle–matrix interface in a model Ni–Al–Ta–Re superalloy

J. Rüsing, N. Wanderka, U. Czubayko, V. Naundorf, D. Mukherji, J. Rösler

Journal:

Scripta Materialia

Year:

2002

Language:

english

File:

PDF, 241 KB

english, 2002

37

Erratum to: Rhenium distribution in the matrix and near the particle–matrix interface in a model Ni–Al–Ta–Re superalloy [Scripta Materialia 46(3) pp. 235–240]

J Rüsing, N Wanderka, U Czubayko, V Naundorf, D Mukherji, J Rösler

Journal:

Scripta Materialia

Year:

2002

Language:

english

File:

PDF, 113 KB

english, 2002

38

Thermal extraction of Pb from the bulk to the surface in Al doped with Pb

D.A. Molodov, U. Czubayko, G. Gottstein, L.S. Shvindlerman

Journal:

Scripta Materialia

Year:

1997

Language:

english

File:

PDF, 1.91 MB

english, 1997

39

Structure of the human heparin-binding growth factor gene pleiotrophin

Shoupeng Lai, Frank Czubayko, Anna Tate Riegel, Anton Wellstein

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 662 KB

english, 1992

40

Mobility of 〈111〉 tilt grain boundaries in the vicinity of the special misorientation ∑=7 in bicrystals of pure aluminium

D.A. Molodov, U. Czubayko, G. Gottstein, L.S. Shvindlerman

Journal:

Scripta Metallurgica et Materialia

Year:

1995

Language:

english

File:

PDF, 417 KB

english, 1995

41

Cytotoxicity of the novel anti-cancer drug rViscumin depends on HER-2 levels in SKOV-3 cells

Shaker Abuharbeid, Jürgen Apel, Martin Sander, Babette Fiedler, Martin Langer, Mary-Lou Zuzarte, Frank Czubayko, Achim Aigner

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 560 KB

english, 2004

42

Sorting nexin 17, a non-self-assembling and a PtdIns(3)P high class affinity protein, interacts with the cerebral cavernous malformation related protein KRIT1

Martin Czubayko, Peter Knauth, Thomas Schlüter, Volker Florian, Ralf Bohnensack

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 599 KB

english, 2006

43

The fibroblast growth factor-binding protein FGF-BP

Shaker Abuharbeid, Frank Czubayko, Achim Aigner

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2006

Language:

english

File:

PDF, 223 KB

english, 2006

44

Efficiency of polyethylenimines and polyethylenimine-graft-poly (ethylene glycol) block copolymers to protect oligonucleotides against enzymatic degradation

Carola Brus, Holger Petersen, Achim Aigner, Frank Czubayko, Thomas Kissel

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

45

Polyethylenimine PEI F25-LMW allows the long-term storage of frozen complexes as fully active reagents in siRNA-mediated gene targeting and DNA delivery

Sabrina Höbel, Robert Prinz, Anastasia Malek, Beata Urban-Klein, Johannes Sitterberg, Udo Bakowsky, Frank Czubayko, Achim Aigner

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2008

Language:

english

File:

PDF, 303 KB

english, 2008

46

Functions of Sorting Nexin 17 Domains and Recognition Motif for P-selectin Trafficking

Peter Knauth, Thomas Schlüter, Martin Czubayko, Cornelia Kirsch, Volker Florian, Susan Schreckenberger, Heidi Hahn, Ralf Bohnensack

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 2.63 MB

english, 2005

47

In vitro cytotoxic and immunomodulatory profiling of low molecular weight polyethylenimines for pulmonary application

Andrea Beyerle, Sabrina Höbel, Frank Czubayko, Holger Schulz, Thomas Kissel, Achim Aigner, Tobias Stoeger

Journal:

Toxicology in Vitro

Year:

2009

Language:

english

File:

PDF, 665 KB

english, 2009

48

Ribozyme targeting of HER-2 inhibits pancreatic cancer cell growth in vivo

A. Thybusch-Bernhardt, A. Aigner, S. Beckmann, F. Czubayko, H. Juhl

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 250 KB

english, 2001

49

The host defence peptide LL-37/hCAP-18 is a growth factor for lung cancer cells

von Haussen, Judith, Koczulla, Rembert, Shaykhiev, Renat, Herr, Christian, Pinkenburg, Olaf, Reimer, Dietlind, Wiewrodt, Rainer, Biesterfeld, Stefan, Aigner, Achim, Czubayko, Frank, Bals, Robert

Journal:

Year:

2008

Language:

english

File:

PDF, 1008 KB

english, 2008

50

Two-photon calcium imaging of evoked activity from L5 somatosensory neurons in vivo

Mittmann, Wolfgang, Wallace, Damian J, Czubayko, Uwe, Herb, Jan T, Schaefer, Andreas T, Looger, Loren L, Denk, Winfried, Kerr, Jason N D

Journal:

Nature Neuroscience

Year:

2011

Language:

english

File:

PDF, 1.81 MB

english, 2011

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